WebJan 12, 2024 · Anisocytosis (high RDW) is typical of iron deficiency, whereas the RDW is usually within reference range in patients with thalassemia (though elevated RDW can occur). (See "Iron deficiency in infants and children <12 years: Screening, prevention, clinical manifestations, and diagnosis" and "Diagnosis of thalassemia (adults and children)".) WebJan 2, 2013 · In iron deficiency, the distribution of iron in the marrow is irregular, resulting in an RBC distribution width (RDW) higher than 17%, whereas in thalassemia minor, the distribution of the genetic defect is perfectly homogeneous, resulting in an RDW lower than 17%. In thalassemia minor the RBC count is usually higher than 5 × 10 6 /μL (5 × ...
Approach to the child with anemia - UpToDate
WebDec 16, 2024 · RDW tests measure the variation in size between blood cells in a given sample. The results of an RDW test can indicate the presence of anemia and some other health conditions. WebAug 14, 2024 · For example, RDW is useful in the differential diagnosis between iron deficiency anaemia and heterozygous thalassemia, whereby RDW is higher in the former … earn $500 fast
MCHC Blood Test Results: Meaning of Low and High Levels
Webadults and higher than 10% in children. The RDW, a measure of variation in the size of the RBC (anisocy-tosis), tends to be above the reference interval in iron deficiency anemias and other microcytic anemias. The RDW in thalassemias is usually within or very close to the reference interval, reflecting the uniformity of red cell size ... WebThe red cell distribution width (RDW) is high in iron deficiency anemia because there is a wide variation in red cell size. In mild thalassemia (alpha or beta), the red cells are strangely all the same size; there is virtually no … WebAnemia is usually suspected based on the history and physical examination. Common symptoms and signs of anemia include. General fatigue. Weakness. Dyspnea on exertion. Pallor. History and physical examination are followed by laboratory testing with a complete blood count, reticulocyte count, and peripheral smear. csv chelmsford