Cisplatin electrolyte

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August undefined, 2024

WebFeb 1, 2024 · Serum electrolytes (particularly potassium), CO 2, creatinine and BUN should be determined frequently during the first few months of Lasix therapy and periodically thereafter. Serum and urine electrolyte determinations are particularly important when the patient is vomiting profusely or receiving parenteral fluids. WebSep 23, 2024 · Cisplatin, a platinum-based antineoplastic agent and a well-known chemotherapeutic drug is the cornerstone for the treatment of many malignancies including bladder, head and neck, lung, ovarian, and testicular cancers. It is effective against various types of cancers, including carcinomas, germ cell tumors, lymphomas, and sarcomas [ 4 ].

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WebMay 24, 2006 · Cisplatin is a well-known nephrotoxic antineoplastic drug. Chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria is one of the … WebJan 12, 2024 · Platinum chemotherapy (Cisplatin), is commonly associated with electrolyte imbalances, including low magnesium (up to 90% using Cisplatin), low potassium, low phosphate, low calcium, and low sodium (up to 43%). This is the type of chemo typically used for lung, colon, ovarian, breast, head/neck, bladder, and testicular cancers. earn token crypto

Cisplatin nephrotoxicity - UpToDate

WebFLUID AND ELECTROLYTE 2 Fluid and electrolyte Question one Edema occurs when excessive fluid surrounds the cells of the human body, leading to cellular edema. The fluid may also accumulate in the collagen-mucopolysaccharide, leading to interstitial edema (Cicardi, et al., 2014). Edema is very detriment because it increases the distance of … WebAbstract. Cisplatin treatment causes tubulointerstitial injury to the kidneys. Common clinical syndromes associated with its use include acute renal failure and a magnesium wasting … WebElectrolyte disturbances were observed after several days of cisplatin administration including changes in levels of sodium, potassium, phosphorus, calcium, and chloride. Clinical observations also identified CP toxicity. ct16r

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WebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude … WebJun 8, 2024 · Cisplatin injection can cause dose-related peripheral neuropathy that becomes more severe with repeated courses of the drug. Neurologic symptoms … ct170WebDrugs & Diseases cisplatin (Rx) Brand and Other Names: Classes: Antineoplastics, Alkylating; Antineoplastics, Platinum Analog Print Dosing & Uses AdultPediatricGeriatric … earntolearn.org

"WebApparently not. It was probably due to the treatment. Also, prior to every chemo treatment, I was not only hydrated, but was given a giant bag of electrolytes, with potassium, … " - Cisplatin electrolyte

Cisplatin electrolyte

WebOxaliplatin Avoid cold drinks/food during administration Vincristine Loss of deep tendon reflexes Constipation Jaw Pain Paclitaxel Premedicate with Benadryl, dexamethasone and an H2-receptor blocker Etoposide Monitor for hypotension Irinotecan Major side … WebSep 15, 2024 · Since its approval in 1979 cisplatin has become one of the most extensively used chemotherapeutics in the clinic and although cell resistance and toxicity hinder its efficacy it continues to be a gold standard regimen. Cisplatin's side effects primarily include nephrotoxicity, gastrointestinal toxicity, neurotoxicity and ototoxicity.

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WebJan 1, 2015 · Background: Cisplatin, one of the most commonly used chemotherapeutic agents, has electrolyte imbalances as one of its most important adverse effects. We conducted this study to characterize... WebCisplatin produces moderate to severe nausea and vomiting in virtually all patients. Nausea and vomiting may start within one hour and may persist for more than 24 hours after chemotherapy. Tolerance may improve with 5-day continuous infusion as compared to rapid, intermittent IV administration.

WebCisplatin 1. NAME 1.1 Substance 1.2 Group 1.3 Synonyms 1.4 Identification Numbers 1.4.1 CAS 1.4.2 Other Numbers 1.5 Brand Names, Trade Names 1.6 Manufacturers, Importers 1.7 Presentation, Formulation 2. SUMMARY 2.1 Main Risks and Target Organs 2.2 Summary of Clinical Effects 2.3 Diagnosis 2.4 First aid measures and management … WebThe proteinuria associated with cisplatin nephrotoxicity is attributed to a tubular defect. 32 Hemolytic uremic syndrome has also been described, especially when cisplatin is combined with bleomycin. 33 Sequential …

WebDec 2, 2014 · Cisplatin is one of the most widely used and highly effective drug for the treatment of various solid tumors; however, it has dose-dependent side effects on the kidney, cochlear, and nerves. Nephrotoxicity is the … WebSep 23, 2024 · Background: Cisplatin is an important drug in the treatment of various Cancers. However, this drug causes nephrotoxicity that is linked to electrolyte …

WebResults: We observed an increase in serum creatinine level to a peak of 1.9 mg/dL (range, 0.8 to 7.8) in the dopamine group, in comparison to 1.4 mg/dL (range, 0.9 to 3.3) in the placebo group (P = .04). Urinary magnesium excretion increased and EGF excretion decreased in both groups.

WebCisplatin is a platinum containing drug first approved as an antineoplastic agent in 1978. It remains an important and effective therapy in many forms of cancer today. … earn togetherWebApr 15, 2024 · Additionally, cisplatin-induced nephrotoxicity led to the unmasking of a familial form of hypomagnesemia. ... Previously, the baseline electrolyte profile was … earn to learn flWebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head and neck, bladder, ovarian, and testicular malignanc Cisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome Federal Practitioner earnt of earnedWebMay 19, 2024 · Electrolyte disorders are also related to cisplatin-induced DNA damage of thiazide-sensitive sodium-chloride co-transporter genes and to the apoptosis of distal tubule cells ( 34 ). Cisplatin treatment may … ct 169 bookWebCisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, … earn to learn scholarship programWebApr 12, 2024 · As previously described, also the cisplatin can induce electrolyte imbalances. In this case, the standard approach to avoid cisplatin-induced nephrotoxicity and the consequent electrolyte alteration is the administration of IV isotonic saline solution in order to stimulate the diuresis. Some authors suggest to add 2 gr of magnesium … ct 16bitWebSep 26, 2024 · While generally mild electrolyte deficiencies are pretty benign, moderate/severe abnormalities can cause many life … earn to free robux