WebApr 10, 2024 · Whether lipoprotein (a) will become a pivotal factor in our search to achieve incremental risk reduction in a broad cohort of patients or remains a niche factor limited to management of young patients at high risk of premature cardiovascular disease is uncertain. WebNov 29, 2024 · Other endpoints will include change in low density lipoprotein cholesterol (LDL-C) and apolipoprotein (B). Apolipoprotein B is a protein found on both LDL and Lp(a). To be eligible for this study, a person must be over 18 years of age, have a lipoprotein (a) > 150 nmol/L, and have known atherosclerotic cardiovascular disease.
The Potential Clinical Benefit of Lowering Lipoprotein(a)
WebJul 1, 2024 · Findings In a mendelian randomization analysis involving more than 80 000 patients and more than 150 000 controls, coronary heart disease risk was proportionally associated with the absolute change in plasma lipoprotein(a) mass concentration; a 101.5-mg/dL change in lipoprotein(a) concentration was associated with the same coronary … WebApr 12, 2024 · Dyslipidemia treatment is of major importance in reducing the risk of atherosclerotic cardiovascular disease (ASCVD), which is still the most common cause of death worldwide. During the last decade, a novel lipid-lowering drug category has emerged, i.e., proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. Apart from the two … hillsborough county google maps
Natural Ways to Lower Lipoprotein (a) Dr. Lauren Deville ...
WebJul 8, 2024 · Statins have neutral or detrimental effects on Lp (a), while PCSK9 inhibitors significantly reduce its level by up to 30%. Specific lowering of Lp (a) with antisense oligonucleotides (ASO) shows good safety and strong efficacy with up to 90% reductions. While the reference range for Lp(a) is considered normal below 30 mg/dl, ideal is under 10. I mentioned herea few approaches to lowering Lp(a) including L-carnitine, estrogen therapy for women, and a high fat diet. But in some cases, the latter two are not feasible, and I haven’t found L-Carnitine by itself to be quite … See more Vitamin C helps to increase production of the protein collagen. We mostly think of collagen as the foundation for skin, from an aesthetic standpoint—but it is also the primary substance … See more When the blood vessels incur damage, binding sites that were previously buried inside the collagen are suddenly exposed. Their purpose is to … See more WebMar 20, 2024 · First, some lipoprotein basics to set the table for the rest of the conversation. Cardiologist Dr. Joel Kahn discusses Lp(a). LDL-C vs. … smart henequen